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Importance Perioperative chemotherapy and surgery are a standard of care for operable gastroesophageal adenocarcinoma. Opal Skaggs.
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Record information. Importance Perioperative chemotherapy and surgery are a standard of care for operable gastroesophageal adenocarcinoma. The Secx Langley and feasibility of adding lapatinib to perioperative chemotherapy should be assessed. Objectives To assess the safety of adding lapatinib to epirubicin, cisplatin, and capecitabine ECX chemotherapy and to establish a recommended dose regimen for a phase 3 trial.
Secx Langley multicenter national trial Langlfy conducted in 29 centers in the United Kingdom in patients with histologically proven, HER2-positive, operable gastroesophageal adenocarcinoma. Data were analyzed May 10,to May 25, No formal comparison between arms was planned.
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